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Rapidly progressive dementia might happen because of: Autoimmune diseases Unusual presentations of more common neurodegenerative diseases (such as Alzheimer’s disease) Prion diseases (rare forms of neurodegenerative disease) Infections Impaired blood flow to or in the brain Exposure to toxic substances Vitamin deficiencies Cancer Toxicity from prescribed medications Recurrent seizures Sometimes certain disorders that cause dementia run in families, which can be considered inherited dementia