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In a March 31, 2025 letter to the National Association of Boards of Pharmacy, the FDA‘s Division of Compounding II told every state board that retatrutide has no United States Pharmacopeia monograph, is not a component of any approved drug, and appears on neither the 503A nor the 503B bulk substances list, so compounded retatrutide qualifies for the exemptions under neither section [2]

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By encouraging the utilization of stored fat for energy, it empowers individuals in their pursuit of a healthy weight, fostering sustainable weight management [8]