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AOD9604 has been studied in pre-clinical cartilage biology and osteoarthritis models , characterising effects on chondrocyte metabolism, proteoglycan synthesis, cartilage matrix preservation, and joint tissue homeostasis that extend beyond the adipose tissue lipolytic biology for which the compound was originally developed

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312 Human neutrophils express FPR1 and FPR2, of which FPR1 binds fMLF specifically and rapidly, whereas FPR2 binds fMLF with low affinity