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We examined methyltransferases that use DNA, RNA, histones and small molecule metabolites as substrates, and tested whether they are able to promote transsulfuration activity (Figures S3E-S3I)

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One was confounded by a second peptide the patient was also injecting, one could not be interpreted because almost no information was reported, and one involved a product that also contained TB-500, where the reaction returned when the patient restarted it but could not be pinned to either peptide.¹ Nobody has run a human pharmacokinetic study for oral, subcutaneous, nasal, or transdermal delivery, despite those being the four routes patients are actually using¹